Baclofen vs Flexeril: How to Pick One for Your Back Pain

Baclofen vs Flexeril: How to Pick One for Your Back Pain

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  • Additionally, do not take Flexeril if you have used a MAO inhibitor such as tranylcypromine, phenelzine, or selegiline within the past two weeks.
  • Skeletal muscle relaxants are widely used in treating musculoskeletal conditions.
  • It is a drug with the brand name of Lioresal that belongs to two groups of drugs known as antispastics and muscle relaxants.
  • Back pain and related musculoskeletal disorders can interfere with daily routines, sleep, job performance, and your ability to enjoy your hobbies.

It is also indicated in spinal cord problems, treating alcoholism, and CNS lesions. There is decreased susceptibility to CNS depression with this antispastic agent. Baclofen, also known as Lioresal, Liofen, or Gablofen, is a gamma-aminobutyric acid (GABA) agonist and belongs to the class of drugs called skeletal muscle relaxants. There’s an oral version of it and one that can be injected directly into the spinal cord. Intrathecal baclofen is FDA-approved for people with moderate to severe spasticity due to traumatic brain injury, spinal cord injury, or other CNS lesion (2, 6). Research is lacking on whether or not antispasmodics are more effective in treating muscle pain and spasms than NSAIDs or acetaminophen.

Note – this medication is not intended to be used for longer than days at a time. If the condition has not improved in this time, talk with your healthcare professional about the most appropriate way to proceed. Note – it does not cure these medical problems, however, this medication may allow other treatment, like – physical therapy, to be more helpful in improving the condition. It is important to note that this formulation should only be used under the supervision of a healthcare professional.

When should I call my healthcare provider?

Your healthcare provider and/or pharmacist will give you specific instructions on how to take the medication. Being high in potassium, raw and unfiltered ACV helps relieve muscle cramps because low potassium levels are one of the common causes of muscle cramps. Additionally, there are a few essential nutrients in ACV which help control the fluid balance in the human body, hence, it prevents dehydration.

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Flexeril is a relatively safe drug, and usually overdoses are not very serious. Although the two are muscle relaxants, their indications are different. The strength of the two depends on the dosage and purpose for which each drug is used, so it isn’t easy to compare the strength of Baclofen vs. Flexeril. Drug information found in the drug comparisons published on is primarily sourced from the FDA drug information.

Diseases & Conditions

For example, providers sometimes prescribe diazepam to treat anxiety and seizures. Now, skeletal muscle relaxants can further be divided into centrally-acting and direct-acting muscle relaxants. Centrally-acting muscle relaxants include cyclobenzaprine, methocarbamol, metaxalone, chlorzoxazone, tizanidine, baclofen, carisoprodol, and orphenadrine. Lioresal is a popular and first-choice treatment for muscle spasticity caused by spinal cord injuries or multiple sclerosis. Apart from the specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal is not the best medicine to take. There are many alternatives available to Baclofen, but they treat only a specific type of muscle pain.

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Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of Flexeril for periods longer than two or three weeks is not recommended. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others.

When taken along with other drugs, it can cause increased suppression of brain function. Particularly taking tricyclic antidepressants with Lioresal may lead to muscle weakness. Monoamine Oxidase Inhibitors, if taken with Baclofen, cause lower blood pressure and marked brain function depression. While taking Lioresal, half-life of flexeril 10 mg alcoholic beverages should be avoided as Gablofen causes drowsiness and dizziness, which can worsen with alcohol intake. Both Flexeril vs. Baclofen can have minor, moderate, or major interactions, leading to extreme side effects or even death. In the past ten years, there have been a few cases of Gablofen abuse.

Muscle relaxers can cause more serious side effects like fainting and blurred vision. Talk to your provider if you experience any bothersome side effects. Epsom salt contains high concentrations of magnesium, an essential electrolyte that helps the muscles function correctly. Therefore, it can be used to ease the stress on the muscles, allowing you to recover faster and relax.

Report Problems to the Food and Drug Administration

It is also injected into the spinal cord (intrathecal) for management of severe spasticity. However, these medications aren’t the first-line therapy for the treatment of pain or spasms. They’re alternative therapy after first- or second-line therapies haven’t worked. This is due to the adverse side effects of antispasmodics, including addiction potential for some types of the medication. Indications Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepressants. Cyclobenzaprine is a tricyclic amine salt that works in the central nervous system CNS as a depressant that reduces muscle hyperactivity.